Supports tissue formation, normal growth and development throughout childhood
• An antioxidant and a factor in the maintenance of good health
• Helps to produce and repair connective tissue
• Aids in the development and maintenance of bones, cartilage, teeth, gums and night vision
• Delicious natural papaya and orange flavour
Children’s Chewable Vitamins provides a combination of vitamins and minerals that help support normal growth and development in children. Niacin, thiamine and biotin provide substrates for energy production in the Krebs cycle, while vitamins B6 and B12 and folate help convert homocysteine into methionine for protein synthesis.1 Approximately 50-60% of magnesium is found in bones, where it stimulates bone forming osteoblast activity and helps in the development and maintenance of bones and teeth.2 Vitamin D helps absorb and use calcium and phosphorus, which are required for normal bone mineralization.3 Daily supplementation with 400 IU of vitamin D helps support bone growth in young children.4 Vitamin C also contributes to the development and maintenance of bones and teeth through its role in collagen synthesis, the primary structural protein found in connective tissue.1 As collagen is also the main protein involved in wound healing, deficiencies in vitamin C may lead to impaired healing of wounds.5 Vitamin A helps maintain the natural barrier of the skin, stimulates immune cell development, and helps maintain eyesight and night vision.6-8 Low levels of vitamin A can affect iron metabolism, which is necessary for hemoglobin production and proper red blood cell activity.9
1. Combs, GF. (2012). The Vitamins (4th ed.). USA: Elsevier.
2. de Baaij, JHF, Hoenderop, JGJ, Bindels, RJM. Physiol Rev. 2015; 95: 1-46.
3. Wranicz, J, Szostak-Wegierek, D. Rocz Panstw Zakl Hig. 2014; 65(3): 179-184.
4. Wagner, CL, Greer, FR. Pediatrics. 2008; 122(5): 1142-1152.
5. Campos, ACL, Groth, AK, Branco, AB. Current Opinion in Clinical Nutrition and Metabolic Care. 2008; 11: 281-288.
6. Mukherjee, S, Date, A, Patravale, V, Korting, HC, Roeder, A, Weindl, G. Clinical Interventions in Aging. 2006; 1(4): 327-348.
7. Ruhl, R. Proceedings of the Nutrition Society. 2007; 66: 458-469.
8. Al Tanoury, Z, Piskunov, A, Rochette-Egly, C. Journal of Lipid Research. 2013; 54: 1761-1775.
9. Oliveira, JM, Michelazzo, FB, Stefanello, J, Rondó, PHC. Nutrition Reviews. 2008; 66(3): 141-147.
Vegan-friendly combination of B vitamins
• Helps the body to form red blood cells and to metabolize carbohydrates, fats, and proteins
• Helps reduce the risk of neural tube defects when taken daily prior to becoming pregnant and during early pregnancy
• Provides 400 mcg of folic acid and 125 mcg of vitamin B12 per 8 drops
• Delicious natural cherry flavour
Bio Folic Acid + B12 Liquid is a vegan-friendly option that helps to prevent vitamin B12 deficiency among vegetarian and vegans, whose diets tend to provide inadequate levels of vitamin B12.1 Both vitamin B12 and folic acid are involved in red blood cell formation and DNA synthesis.2,3 Vitamin B12 and folic acid are also required for the conversion of homocysteine to methionine, which is necessary for the production of S-adenosyl-methionine, the methyl donor involved in nearly all methylation reactions.4,5 Research demonstrates that daily supplementation with 400 mcg of folic acid during the first trimester helps to decrease neural tube defects by approximately 50%.6 In a randomized, placebo-controlled trial involving 119 pregnant women, continued supplementation with 400 mcg of folic acid daily into the second and third trimesters significantly increased maternal and cord blood folate status.7 Folic acid intake also better maintained homocysteine levels in the late stages of pregnancy, which may be associated with appropriate methyl transfer activity.5,7
1. Briani, C, Dalla Torre, C, Citton, V, Manara, R, Pompanin, S, Binotto, G, Adami, F. Nutrients. 2013; 5: 4521-4539.
2. Fenech, M. Mutation Research. 2012; 733: 21- 33.
3. Combs, GF. (2012). The Vitamins. USA: Elsevier.
4. Czeizel, AE, Dudàs, I, Vereczkey, A, Bànhidy, F. Nutrients. 2013; 5: 4760-4775.
5. Imbard, A, Benoist, JF, Blom, HJ. Int. J. Environ. Res. Public Health. 2013; 10: 4352-4389.
6. Osterhues, A, Ali, NS, Michels, KB. Critical Reviews in Food Science and Nutrition. 2013; 53: 1180-1190.
7. McNulty, B, McNulty, H, Marshall, B, Ward, M, Molloy, AM, Scott, JM, Dornan, J, Pentieva, K. Am J Clin Nutr. 2013; 98: 92-98.